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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
6.67
Human Site:
Y632
Identified Species:
11.28
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
Y632
Y
P
P
H
Q
P
A
Y
L
L
P
P
R
P
D
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
Y632
Y
P
P
H
Q
P
A
Y
L
L
P
P
R
P
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
T368
S
S
S
H
F
R
G
T
D
S
N
Y
P
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
P685
F
P
P
L
P
P
P
P
P
P
P
P
P
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
P325
F
K
V
K
R
K
E
P
P
E
A
A
S
S
G
Chicken
Gallus gallus
Q5F3P8
2008
223067
F700
P
P
P
P
Q
P
A
F
P
M
P
P
P
L
P
Frog
Xenopus laevis
Q66J90
1938
216239
G652
V
I
P
I
L
P
P
G
F
P
P
L
P
P
P
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
H680
P
S
H
H
P
M
L
H
P
L
H
S
Y
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P630
S
L
S
S
Q
E
D
P
I
Q
T
K
E
G
A
Honey Bee
Apis mellifera
XP_395451
1406
159180
E444
S
Y
S
P
A
P
D
E
I
E
P
E
P
P
K
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
V545
S
S
T
H
T
N
S
V
P
N
L
K
S
H
E
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
P717
L
P
S
Q
P
F
P
P
G
V
Q
E
A
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
S118
V
H
N
T
L
A
S
S
S
G
S
L
P
T
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
S351
Y
K
D
S
K
P
T
S
S
R
P
V
P
V
P
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
6.6
N.A.
33.3
N.A.
N.A.
0
46.6
26.6
13.3
N.A.
6.6
20
6.6
13.3
P-Site Similarity:
100
100
N.A.
6.6
N.A.
40
N.A.
N.A.
13.3
60
26.6
20
N.A.
13.3
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
22
0
0
0
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
15
0
8
0
0
0
0
0
15
% D
% Glu:
0
0
0
0
0
8
8
8
0
15
0
15
8
0
15
% E
% Phe:
15
0
0
0
8
8
0
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
8
8
0
0
0
15
8
% G
% His:
0
8
8
36
0
0
0
8
0
0
8
0
0
8
0
% H
% Ile:
0
8
0
8
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
15
0
8
8
8
0
0
0
0
0
15
0
0
8
% K
% Leu:
8
8
0
8
15
0
8
0
15
22
8
15
0
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
0
0
0
8
8
0
0
0
0
% N
% Pro:
15
36
36
15
22
50
22
29
36
15
50
29
50
36
29
% P
% Gln:
0
0
0
8
29
0
0
0
0
8
8
0
0
8
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
8
0
0
15
0
0
% R
% Ser:
29
22
29
15
0
0
15
15
15
8
8
8
15
8
0
% S
% Thr:
0
0
8
8
8
0
8
8
0
0
8
0
0
8
0
% T
% Val:
15
0
8
0
0
0
0
8
0
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
22
8
0
0
0
0
0
15
0
0
0
8
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _